Aging May Influence The Composition Of Gut Bacteria, Study Finds

A new study indicates that aging causes significant changes in the microbiome of the human small intestine, and that the changes are different from those caused by drugs or disease. The researchers mainly relied on fecal samples to explore the gut microbiome and its impact on health. However, the study’s principal investigator, Dr Ruchi Mathur, noted that fecal samples alone do not represent the entire gut. The results of the study, conducted by Cedars-Sinai Medical Center in the United States, were published in the journal Cell Reports.

“By uncovering the microbial changes that occur in the small intestine with age, drug use, and disease, we hope to identify unique components of the microbial community to target for therapies and interventions that could promote a healthy aging, ”said Dr. Mathur. .

Researchers in Cedars-Sinai’s Medically Associated Science and Technology (MAST) program looked at the microbiome and its relationship to aging. They analyzed fecal samples from the small intestine which is typically around 20 feet long and has the absorption surface of a tennis court.

According to Dr Mathur, the participants, whose fecal samples were tested, were between the ages of 18 and 80. She said that through this one-of-a-kind study, they came to the conclusion that, like drugs and disease, aging also influences changes in the microbial makeup of the small intestine.

The study is important because billions of gut bacteria, fungi, and viruses can play crucial roles in human health and disease. Scientists have also focused on this question as the 21st century is called “the era of the gut microbiome”.

Various studies have suggested that changes in microbial composition can affect a person’s health and can even lead to serious illnesses like gastroenterological disease, diabetes, and obesity.

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