Composition – F-BOD http://f-bod.com/ Sun, 19 Sep 2021 13:24:16 +0000 en-US hourly 1 https://wordpress.org/?v=5.8 https://f-bod.com/wp-content/uploads/2021/09/fbod-150x150.png Composition – F-BOD http://f-bod.com/ 32 32 What you need to know about the investor mix of TUI AG (ETR: TUI1) https://f-bod.com/what-you-need-to-know-about-the-investor-mix-of-tui-ag-etr-tui1/ Sun, 19 Sep 2021 07:58:02 +0000 https://f-bod.com/what-you-need-to-know-about-the-investor-mix-of-tui-ag-etr-tui1/ The large shareholder groups of TUI AG (ETR: TUI1) have power over the company. Large companies usually have institutions as shareholders, and we usually see insiders holding shares in smaller companies. Companies that have been privatized tend to have low insider ownership. TUI has a market cap of 3.9 billion euros, so it’s too big […]]]>

The large shareholder groups of TUI AG (ETR: TUI1) have power over the company. Large companies usually have institutions as shareholders, and we usually see insiders holding shares in smaller companies. Companies that have been privatized tend to have low insider ownership.

TUI has a market cap of 3.9 billion euros, so it’s too big to go unnoticed. We expect institutions and retail investors to own a portion of the company. Our analysis of company ownership, below, shows that institutions own shares in the company. Let’s dig deeper into each type of owner, to find out more about TUI.

See our latest review for TUI

XTRA ownership breakdown: TUI1 September 19, 2021

What does institutional ownership tell us about TUI?

Institutions typically measure themselves against a benchmark when reporting to their own investors, so they often become more enthusiastic about a stock once it’s included in a major index. . We would expect most businesses to have some institutions listed, especially if they are growing.

TUI already has institutions on the share register. Indeed, they hold a respectable stake in the company. This implies that analysts working for these institutions have reviewed the action and appreciate it. But like everyone else, they can be wrong. When several institutions hold a stock, there is always a risk that they are in a “crowded trade”. When such a transaction goes awry, several parties may compete with each other to sell stocks quickly. This risk is higher in a company with no history of growth. You can see TUI’s historical revenue and income below, but keep in mind that there is always more to tell.

profit and revenue growth
XTRA: TUI1 Earnings and Revenue Growth September 19, 2021

We note that hedge funds do not have a significant investment in TUI. Unifirm Limited is currently the largest shareholder of the company with 30% of the shares outstanding. Meanwhile, the second and third largest shareholders hold 3.0% and 1.9% of the outstanding shares, respectively.

A closer look at our ownership data shows that the top 25 shareholders collectively own less than half of the ledger, suggesting a large group of small holders where no shareholder has a majority.

While studying the institutional ownership of a company can add value to your research, it is also recommended that you research analyst recommendations to better understand the expected performance of a stock. Many analysts cover the stock, so it can be interesting to see what they are forecasting as well.

TUI insider ownership

While the precise definition of an insider can be subjective, almost everyone considers board members to be insiders. The management ultimately reports to the board of directors. However, it is not uncommon for managers to be board members, especially if they are founders or CEOs.

Most view insider ownership as a positive, as it can indicate that the board is well aligned with other shareholders. However, on some occasions too much power is concentrated within this group.

We can see that the insiders own shares in TUI AG. It’s a big company, so it’s good to see that level of alignment. Insiders own 67 million euros in shares (at current prices). Most would say it shows the alignment of interests between shareholders and the board. Still, it might be worth checking out if these insiders have sold.

General public property

The general public has a substantial 59% stake in TUI, which suggests that it is a fairly popular stock. This size of property gives mainstream investors some collective power. They can and probably do influence decisions about executive compensation, dividend policies and proposed business acquisitions.

Owned by a private company

It appears that private companies own 32% of TUI’s shares. It is difficult to draw conclusions from this fact alone, so it is worth considering who owns these private companies. Sometimes insiders or other related parties have an interest in shares of a public company through a separate private company.

Next steps:

It’s always worth thinking about the different groups that own shares in a company. But to understand TUI better, there are many other factors to consider. Take risks for example – TUI has 4 warning signs (and 2 which are a bit disturbing) we think you should be aware of.

Ultimately the future is the most important. You can access this free analyst forecast report for the company.

NB: The figures in this article are calculated from data for the last twelve months, which refer to the 12-month period ending on the last date of the month of date of the financial statement. This may not be consistent with the figures in the annual report for the entire year.

If you are looking to trade TUI, open an account with the cheapest * professional approved platform, Interactive Brokers. Their clients from more than 200 countries and territories trade stocks, options, futures, currencies, bonds and funds around the world from a single integrated account. Promoted

This Simply Wall St article is general in nature. We provide commentary based on historical data and analyst forecasts using only unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell shares and does not take into account your goals or your financial situation. Our aim is to bring you long-term, targeted analysis based on fundamental data. Note that our analysis may not take into account the latest announcements from price sensitive companies or qualitative documents. Simply Wall St has no position in the mentioned stocks.
*Interactive Brokers Ranked Least Expensive Broker By StockBrokers.com Online Annual Review 2020

Do you have any feedback on this item? Are you worried about the content? Get in touch with us directly. You can also send an email to the editorial team (at) simplywallst.com.


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Qualitative analysis of key players and competitive industry scenario, 2026 https://f-bod.com/qualitative-analysis-of-key-players-and-competitive-industry-scenario-2026/ Sat, 18 Sep 2021 19:18:45 +0000 https://f-bod.com/qualitative-analysis-of-key-players-and-competitive-industry-scenario-2026/ Growth Forecast Report on ‘Software Composition Analysis Market Size | Industry Segment by Applications (BFSI, Government & Defense, IT & Telecommunications, Healthcare, Retail & E-Commerce, Automotive, Manufacturing, Others, by Region, North America, United States, Canada, Europe, Germany, France, United Kingdom, Italy and R), By Type (Cloud Based & On-Premises), Regional Outlook, Market Demand, Latest Trends, […]]]>

Growth Forecast Report on ‘Software Composition Analysis Market Size | Industry Segment by Applications (BFSI, Government & Defense, IT & Telecommunications, Healthcare, Retail & E-Commerce, Automotive, Manufacturing, Others, by Region, North America, United States, Canada, Europe, Germany, France, United Kingdom, Italy and R), By Type (Cloud Based & On-Premises), Regional Outlook, Market Demand, Latest Trends, Growth and Revenue of Product Composition Analysis industry Software by Manufacturers, Company Profiles, Growth Forecast – 2026. ”Analyzes the current market size and next 5 years growth of this industry.

The Software Composition Analysis Market report first introduced the basics: definitions, classifications, applications, and market overview; Product specifications; manufacturing process; cost structures, raw materials, etc. Then, it analyzed the main market conditions of the region of the world including product price, profit, capacity, production, supply, demand and market growth rate and forecast etc. . Ultimately, the Software Composition Analysis Market report introduced new project SWOT analysis, investment feasibility analysis, and ROI analysis.

This study has been analyzed and takes into account the market CAGR, valuation, volume, revenue (historical and forecast), sales (current and future), and other key factors related to the global analysis market the composition of the software.

Request a copy of this report @ https://www.nwdiamondnotes.com/request-sample/13728

Primitive manufacturers involved in the Software Composition Analysis Market report:

  • WhiteSource Software Black Duck Software Synopsys Broadcom Sonatype WhiteHat Security Flexera NexB SourceClear Rogue Wave Software

The objectives of the study of the Specialty Oleochemicals Market report are:

  • To analyze and research the United States, European Union Software Composition Analysis market status and future forecast involving Sales, Value (Revenue), Growth Rate (CAGR), market share, history and forecasts.
  • To introduce the Software Composition Analysis manufacturers, to introduce the major players sales, revenue, market share and recent development.
  • To divide distribution data by regions, types, companies, and applications
  • To analyze the potential and benefit of the global market and key regions of the analysis of software composition, opportunities and challenges, restraints and risks.
  • Identify important trends, drivers and influencing factors in the world and regions
  • To analyze competitive developments such as extensions, agreements, new product launches, and acquisitions in the Software Composition Analysis market.

By product type, the market is mainly divided into:

  • Cloud-based and on-premise

By Applications product, the market is mainly divided into:

  • BFSI
  • Government & Defense
  • IT & Telecom
  • Health care
  • Retail and e-commerce
  • Automotive
  • Manufacturing
  • Others
  • By region
  • North America
  • we
  • Canada
  • Europe
  • Germany
  • France
  • UK
  • Italy and R

Global Software Composition Analysis Market presents critical insights and factual data on the Software Composition Analysis industry, with an overall statistical study of this market based on market drivers , the limits of the market and its future prospects. Widespread trends and opportunities are also considered in the Software Composition Analysis market research.

Key points describing various features of the report: –

Manufacturing analysis – The Software Composition Analysis Market contains a section presenting the examination of authorized manufacturing processes by means of vital data gathered through industry specialists and key authorities of profiled organizations.

Competition in the remote diagnostics market – Leading Professionals were reviewed based on their Company Profile, Product Database, Ability, Product / Service Value, Transactions, and Cost / Revenue.

Demand and supply and efficiency – The Software Composition Analysis industry report further provides distribution, production, consumption, and EXIM (Export and Import).

What this Software Composition Analysis Industry research report offers:

  • Global Analysis of Software Composition Market size, share assessments for regional and country segments.
  • Global market changes, drivers, restraints, growth opportunities, threats, challenges, investment opportunities and recommendations.
  • 5-6 Years Software Composition Analysis market forecast along with historical data of all mentioned segments, sub-segments, and regional markets.
  • Competitive landscape mapping with the main trends.
  • Profiling of large companies with their detailed policies, financial data and recent developments.
  • Strategic recommendations for new companies and start-ups.
  • Supply chain movements mapping the latest technological advancements.
  • Strategic approvals in business lines based on market assessments.

Request customization on this report @ https://www.nwdiamondnotes.com/request-for-customization/13728


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Freedom Under Law Raises Concerns Over Composition of Selection Panel for New Chief Justice https://f-bod.com/freedom-under-law-raises-concerns-over-composition-of-selection-panel-for-new-chief-justice/ Fri, 17 Sep 2021 17:53:55 +0000 https://f-bod.com/freedom-under-law-raises-concerns-over-composition-of-selection-panel-for-new-chief-justice/ President Cyril Ramaphosa and Chief Justice Mogoeng Mogoeng. Chief Justice Mogoeng Mogoeng’s term will end on October 11. President Cyril Ramaphosa called on the public to appoint South Africa’s next chief justice to promote transparency. Freedom Under Law raised several concerns, such as the inclusion of political figures in the panel. Freedom Under Law (FUL) […]]]>

President Cyril Ramaphosa and Chief Justice Mogoeng Mogoeng.

  • Chief Justice Mogoeng Mogoeng’s term will end on October 11.
  • President Cyril Ramaphosa called on the public to appoint South Africa’s next chief justice to promote transparency.
  • Freedom Under Law raised several concerns, such as the inclusion of political figures in the panel.

Freedom Under Law (FUL) says while taking note of President Cyril Ramaphosa’s decision to invite the public to participate in the selection of South Africa’s next Chief Justice, it has several concerns about the composition of the appointed panel. to shortlist the candidates.

Ramaphosa initially called on the public to appoint South Africa’s next chief justice to promote transparency.

In a statement released Friday, FUL CEO Nicole Fritz said the panel was made up of several “exceptional” individuals who had played distinguished roles in South Africa and abroad.

“However, the inclusion of political appointments is not welcome. The inclusion of two political appointments from the same political party is particularly against any principle,” she said.

READ | Chief Justice Mogoeng’s “long leave” is due, not unusual, his office says

“Furthermore, the failure to include a senior or recently retired judge means that first-hand knowledge of the current functioning of South African justice is excluded. Senior lawyers are also not represented in the panel, again excluding those who have [a] thorough understanding of current issues faced by the judiciary as a whole and with first-hand knowledge of individual candidates.

In short, the committee is insufficiently balanced in its composition and does not rely on the best available knowledge on the current state and needs of the judiciary. This is unlikely to generate the level of public trust essential to the process.

Chief Justice Mogoeng Mogoeng has less than a month before the end of his term, which ends on October 11.

On Thursday, the presidency announced that anyone would be able to nominate a candidate.

An application must be accompanied by the approval and support of at least one professional body of lawyers or NGOs working in the field of human rights or other legal fields.

All nominations will be made public on the Presidency website and any objection should be sent in writing by October 15.

A panel chaired by Navi Pillay, the former judge of the International Court of Justice and United Nations High Commissioner for Human Rights, will then shortlist between three and five candidates for consideration by the president.

The panel also includes Justice and Corrections Minister Ronald Lamola, former Justice Minister Jeff Radebe, former Public Protector Advocate Thuli Madonsela, SA Mmapaseka National AIDS Council Co-Chair Steve Letsike and Professor Ziyad Motala of Howard University Law School.


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THE INSIDER: Intrigues at the Supreme Court on the composition of the “VAT panel” https://f-bod.com/the-insider-intrigues-at-the-supreme-court-on-the-composition-of-the-vat-panel/ Fri, 17 Sep 2021 07:35:00 +0000 https://f-bod.com/the-insider-intrigues-at-the-supreme-court-on-the-composition-of-the-vat-panel/ The legal battle over value added tax (VAT) has moved to the Supreme Court with intense internal intrigue over choosing panel members to hear the Rivers State government’s appeal, said insiders at TheCable. Judge Stephen Pam of the Federal High Court, Port Harcourt Division, Rivers State, ruled that states should collect VAT. Under current practice, […]]]>

The legal battle over value added tax (VAT) has moved to the Supreme Court with intense internal intrigue over choosing panel members to hear the Rivers State government’s appeal, said insiders at TheCable.

Judge Stephen Pam of the Federal High Court, Port Harcourt Division, Rivers State, ruled that states should collect VAT.

Under current practice, VAT is collected on behalf of the federation by the Federal Inland Revenue Service (FIRS), with states enjoying a 30 percent bypass.

Rivers, Lagos and Ogun states have enacted laws to enforce the judgment, but the appeals court asked them to stay the action until the appeal, filed by FIRS, is determined.

However, Rivers State moved to the Supreme Court, asking that the appellate court’s order be set aside.

MUHAMMAD GOING ON HOLIDAY?

Supreme Court insiders told TheCable on Thursday that there were plans to organize a trip to the UK for Ibrahim Tanko Muhammad, the federation’s chief justice, before a panel was formed to rule on the ‘call.

In her absence, Mary Odili, number 2 in the Supreme Court hierarchy and former first lady of Rivers State, will appoint the panel.

A statement from the seven-member panel will be the final word on the VAT controversy.

Muhammad has not been active since his fall sick with COVID Last year.

He was flown to Dubai, United Arab Emirates, for treatment.

In its appeal, the Rivers State government asked the Supreme Court to overturn the appeals court’s decision and set up a new panel.


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OSCE States Eligible to Change the Composition of Observation Groups – Russian Representative https://f-bod.com/osce-states-eligible-to-change-the-composition-of-observation-groups-russian-representative/ Thu, 16 Sep 2021 18:49:13 +0000 https://f-bod.com/osce-states-eligible-to-change-the-composition-of-observation-groups-russian-representative/ Participating countries of the Organization for Security and Co-operation in Europe (OSCE) have the right to adjust the composition of observer missions, said on Thursday Alexander Lukachevich, permanent representative of Russia to the organization, commenting the refusal of the OSCE Parliamentary Assembly to observe the elections to the Russian parliament VIENNA (UrduPoint News / Spoutnik […]]]>

Participating countries of the Organization for Security and Co-operation in Europe (OSCE) have the right to adjust the composition of observer missions, said on Thursday Alexander Lukachevich, permanent representative of Russia to the organization, commenting the refusal of the OSCE Parliamentary Assembly to observe the elections to the Russian parliament

VIENNA (UrduPoint News / Spoutnik – September 16, 2021) Participating countries of the Organization for Security and Cooperation in Europe (OSCE) have the right to adjust the composition of observer missions, said Alexander Lukashevich, permanent representative from Russia to the organization. Thursday, commenting on the OSCE Parliamentary Assembly’s refusal to observe the Russian parliamentary elections.

Earlier in August, the OSCE announced that it would not send its observers to Russia because Moscow asked to reduce their numbers due to the COVID-19 pandemic.

“Unfortunately, some people in this room are unaware that participating States have every right to adjust the composition of observer missions, and the OSCE Parliamentary Assembly and ODIHR (Office for Democratic Institutions and Rights human) should at least meet the established parameters. monitoring of national elections, especially in the midst of the pandemic, ”Lukachevich told the OSCE Permanent Council, responding to remarks on the issue by Margareta Cederfelt, chairperson of the OSCE Parliamentary Assembly.

The OSCE position shows “either blatant incompetence or attempts to use OSCE tools to interfere in the internal affairs of states,” he added.

Russian parliamentary elections will take place from September 17 to 19. The lower house of parliament, the State Duma, is elected for a five-year term under a mixed electoral system. 225 lawmakers are elected from party lists and another 225 from single-term constituencies in a single round.


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Cromwell management disrupts board composition https://f-bod.com/cromwell-management-disrupts-board-composition/ Thu, 16 Sep 2021 01:46:32 +0000 https://f-bod.com/cromwell-management-disrupts-board-composition/ Ooi Eng Peng will become a new non-independent director for CERIT. In an ad posted via SGX, Cromwell European Real Estate Investment Trust (CEREIT) revealed changes in the current composition of the board of directors of Cromwell EREIT Management Pte. Ltd. Ooi Eng Peng, is expected to replace Michael Wilde as a non-independent non-executive director. […]]]>

Ooi Eng Peng will become a new non-independent director for CERIT.

In an ad posted via SGX, Cromwell European Real Estate Investment Trust (CEREIT) revealed changes in the current composition of the board of directors of Cromwell EREIT Management Pte. Ltd.

Ooi Eng Peng, is expected to replace Michael Wilde as a non-independent non-executive director. This will take effect on September 15, 2021.

Ooi is currently non-executive vice-chairman of the board of directors of the manager of CEREIT.

Previously, Ooi had over 35 years of real estate experience, which includes real estate investing, development, project management, fund management and management in Australia and Asia. Notable positions he has held include CFO, Global Chief Financial Officer and Asia CEO for Lendlease as well as Asia CEO for Lendlease Investment Management and Retail.

After retiring from his executive career, Ooi also extended his experience across entities in the Asia-Pacific region. He has held positions in ESR Funds Management, ESR-REIT and Savant Global Capital Pty. Ltd.

He also holds a Bachelor of Commerce degree and is currently a member of the Certified Practicing Accountants of Australia, as well as a member of the Singapore Institute of Directors.

Lim Swe Guan, President of CEREIT, shared his reactions to Eng Peng’s arrival on the board.

“We are delighted that Eng Peng is joining the board of directors. The manager will benefit from Eng Peng’s extensive experience in the real estate industry and the strong and continued alignment and support of the CEREIT sponsor. Eng Peng’s skill set will further increase the expertise and diversity already enjoyed by the current board of directors, overseeing CEREIT’s strategy and governance to deliver sustainable and growing returns to unitholders over the long term. term.

Michael Wilde will resume his role as CFO of Cromwell Property Group.

This appointment has been approved by the Monetary Authority of Singapore (MAS).


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Breakthrough heights of the yacht antenna market by 2028 | Technology composition AirMar, Promarine Technologies, Scout Technologies, Simrad Systems, Shakespeare Systems, B & G Sailing, KNS, Navisystems, EPak, ELNA, West Marine https://f-bod.com/breakthrough-heights-of-the-yacht-antenna-market-by-2028-technology-composition-airmar-promarine-technologies-scout-technologies-simrad-systems-shakespeare-systems-b-g-sailing-kns-navisyst/ Tue, 14 Sep 2021 11:58:37 +0000 https://f-bod.com/breakthrough-heights-of-the-yacht-antenna-market-by-2028-technology-composition-airmar-promarine-technologies-scout-technologies-simrad-systems-shakespeare-systems-b-g-sailing-kns-navisyst/ The main purpose of a yacht antenna is to provide a radiator for the power produced by the radio transmitter and to radiate that energy in the right direction. VHF and UHF antennas use very high frequency (VHF) and ultra high frequency (UHF) signals for two-way radio, public safety and commercial communications. These multipolarized antennas […]]]>

The main purpose of a yacht antenna is to provide a radiator for the power produced by the radio transmitter and to radiate that energy in the right direction.

VHF and UHF antennas use very high frequency (VHF) and ultra high frequency (UHF) signals for two-way radio, public safety and commercial communications. These multipolarized antennas from MP Antenna reduce signal degradation and provide users with more consistent voice and data communications.

The high quality audio on FM radio and some TV stations can be traced to the VHF band. Marine VHF antennas can be used to receive two-way communications and weather band signals. Additionally, unlike AM or UHF, VHF can also receive VHF TV stations and FM radio.

For a motor boat under 24 feet or a sailboat, a 3 dB antenna is recommended. Usually a 6 dB antenna is recommended for boats over 24 feet and a 9 dB antenna is recommended for boats over 32 feet.

Request a copy of the report @ https://www.reportconsultant.com/request_sample.php?id=91024

The major players featured in the report include:

Composition of AirMar technology, Promarine Technologies, Scout Technologies, Simrad Systems, Shakespeare Systems, B & G Sailing, KNS, Navisystems, EPak, ELNA, West Marine

The aim of the report is to help relevant players to decipher the essential clues about the various real-time developments based on the market, also pulling important references from historical data, to possibly present a forecast and prediction of highly efficient market, fostering a sustainable position and impeccable income stream. despite challenges such as sudden pandemic, disrupted production, and disrupted sales channel in the Yacht Antenna market.

This research report is an amalgamation of all relevant data relating to historical and current market specific information that systematically decides on the future growth prospects of the Yacht Antenna Market. This section of the report further aims to enlighten the readers of the report on the decisive developments and catastrophic implications caused by an unprecedented incident such as the pandemic which has visibly rendered unprecedented implications in the market.

Get up to 40% off the report @ https://www.reportconsultant.com/ask_for_discount.php?id=91024

Market segmentation :

By type of vessel / vessel infrastructure volume

  • 75 to 120 feet
  • 121 to 250 feet
  • Above 250 feet

By component type

  • Based on hardware components
  • Based on software components

By type of product technology

  • RADAR
  • SONAR
  • GPS
  • Other display-based sensors

By type of application

  • Navigation
  • Communication
  • Automating
  • Security
  • Entertainment

This report is well-researched to present a crucial analytical review affecting the Yacht Antennas market amid the COVID-19 outrage. The report is thus designed to offer a versatile understanding of the various influencers of the market, encompassing an in-depth analysis of the barriers as well as a mapping of the opportunities which together decide on the future growth trajectory of the market. In light of the lingering COVID-19 pandemic, this carefully crafted research offering is in perfect sync with current market developments as well as challenges which together exert a tangible influence on the holistic growth trajectory of the market. Yacht antenna.

In addition to presenting an insightful overview of historical and current market specific developments inclined to aid a future-ready business decision, this well-compiled research report on the Yacht Antenna Market also presents essential details on various best practices. industry including SWOT and PESTEL analysis to properly locate and maneuver the scope of benefits. Therefore, to enable and influence a flawless market-specific business decision, aligning with industry best practices, this market-specific research report also provides a systematic overview of vital growth triggers comprising of Market opportunities, obstacles and lingering challenges of the market, also presenting a comprehensive perspective of the various drivers and threats that end up influencing the growth trajectory of the Yacht Antennas market.

The geographical segmentation of the yacht antenna includes:

– North America (United States, Canada, Mexico)

– Europe (UK, France, Germany, Spain, Italy, Central and Eastern Europe, CIS)

– Asia-Pacific (China, Japan, South Korea, ASEAN, India, rest of Asia-Pacific)

– Latin America (Brazil, rest of LA)

– Middle East and Africa (Turkey, CCG, rest of Middle East)

Some major points of the COT:

Chapter 1. Presentation of the report

Chapter 2. Growth trends

Chapter 3. Market Share by Major Players

Chapter 4. Data breakdown by type and application

Chapter 5. Market by End-users / Application

Chapter 6. COVID-19 Outbreak: Impact on Yacht Antenna Industry

Chapter 7. Analysis of opportunities in the Covid-19 crisis

Chapter 9. Driving force of the market

And more…

In this latest research post, a comprehensive overview of the current market scenario has been presented, with the aim of helping market players, stakeholders, research analysts, industry veterans and others to borrow money. insightful clues to this ready-made market research report, thus influencing definitive business discretion. The report in its following sections also presents a detailed overview of the competition spectrum, profiling key players and their thoughtful business decisions influencing the growth of the Yacht Antennas market.

About Us:

Report Consultant – A global pioneer in analytics, research and consulting who can help you renovate your business and change your approach. With us, you will learn how to make fearless decisions taking calculated risks leading to lucrative business in an ever-changing market. We make sense of downsides, opportunities, circumstances, estimates and information using our experienced skills and verified methodologies.

Our research reports will give you the most realistic and incomparable experience of revolutionary market solutions. We have effectively led business around the world through our market research reports thanks to our predictive nature and are uniquely positioned to lead digital transformations. Thus, we create greater value for clients by presenting progressive opportunities in the futuristic market.

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(Report consultant)

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Musician Jonathan Paul Smith’s unique lineup dominates digital media https://f-bod.com/musician-jonathan-paul-smiths-unique-lineup-dominates-digital-media/ Sat, 11 Sep 2021 15:39:28 +0000 https://f-bod.com/musician-jonathan-paul-smiths-unique-lineup-dominates-digital-media/ “To be irreplaceable, you must always be different. ” – Coco Chanel Succeeding in an industry oversaturated with young talent is a challenge. The music industry has reached a different stature with the advent of social media. The universal platform that social media has offered to artists and creators around the world has opened a […]]]>

“To be irreplaceable, you must always be different. ” – Coco Chanel

Succeeding in an industry oversaturated with young talent is a challenge. The music industry has reached a different stature with the advent of social media. The universal platform that social media has offered to artists and creators around the world has opened a gateway of opportunity. With a large audience from all corners of the globe, all forms of creativity have found their place on social networks. Growth has been particularly remarkable in the music industry. Musicians and singers no longer depend on labels to find their audience. They create, publish and find recognition themselves.

This is how musician Jonathan Paul Smith carved out his place in the music industry. He is famous for his transgender compositions which harmoniously blend hip-hop with undertones of jazz and rock. His music is both energetic and calming. What sets him apart from his contemporaries is his characteristic style of incorporating natural sounds into the background of his compositions. It creates a haunting amalgamation of everyday sounds that we hear every now and then, but which had never caught our ears before.

His creativity in merging natural sound and instrumental music has a lot to do with his intense passion for sounds. As a child, Jonathan was always drawn to the sounds of his surroundings. Something like the horn of a car, drops of water and the buzz of bees were music to his ears. He realized his passion for sound at the age of 5 when he heard his teacher walking down an empty hallway. The rhythmic sound of the clip-clopping of the heels immediately captivated her artistic spirit. He has since developed a remarkable ear for the sounds that surround him.

In addition to listening to these sounds, Jonathan also began to imitate them in different ways. After years of practice, he has succeeded in creating the sound of an opening bottle and the buzz of a bee. He used his tongue, cheek, lips and hands to perfectly mimic natural sounds. This not only makes his music melodic, but also unique.

He started his career performing in shows, parties and clubs. His euphonic voice caught the attention of audiences, making him a sought-after artist in New York City. Her life began to deteriorate during the pandemic-related lockdown when all live events were called off. During this time, Jonathan was unemployed for several months. But once his career was reached, he decided to bounce back on social media. He launched his YouTube channel Moving sound with her first single “Times Will Change” in October 2020.

“Times Will Change” became an instant hit on social media. It marked the start of a new wave of cross-genre tracks with a brilliant backdrop of natural sound effects. The song received 2 million views in a month and even topped the Spotify charts. “Times Will Change” made Jonathan an overnight star, bigger than he has ever been in the music industry as a performing artist.

There has been no turning back since then. He went on to release consecutive hits, taking the internet by storm with his unique soul music. He is now preparing to enter the mainstream music industry with his natural talent and love for sound.


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Composition of gut flora may impact susceptibility to konzo, a neurological disease caused by cassava, a global staple crop https://f-bod.com/composition-of-gut-flora-may-impact-susceptibility-to-konzo-a-neurological-disease-caused-by-cassava-a-global-staple-crop/ Fri, 10 Sep 2021 09:21:45 +0000 https://f-bod.com/composition-of-gut-flora-may-impact-susceptibility-to-konzo-a-neurological-disease-caused-by-cassava-a-global-staple-crop/ Nature Communications i> (2021). “width =” 800 “height =” 529 “” /> From left to right: Dr Nicole Mashkano and Dr Matthew Bramble. Dr Mashkano is leading an effort to teach individuals in various health zones how to get wet in Kahemba. The wetting method is used as an additional step to further detoxify the […]]]>
Nature Communications i> (2021). “width =” 800 “height =” 529 “” />

From left to right: Dr Nicole Mashkano and Dr Matthew Bramble. Dr Mashkano is leading an effort to teach individuals in various health zones how to get wet in Kahemba. The wetting method is used as an additional step to further detoxify the toxins from the cassava flour before consumption. Here, Dr Mashkano and Dr Bramble spread a wet mixture of cassava powder and water on a thin layer of tarp, dried it in the sun, then decompose and release hydrogen cyanide as a gas of hydrogen cyanide. Credit: Brambel et al. National Children’s Hospital, Nature Communication (2021).

According to a study of 180 children, the genetic differences between the gut microbiota and conzo-prone areas in the Democratic Republic of Congo (DRC) are cyanide after consuming contracted cassava. May affect the output of. Cassava is a food secure crop for over 500 million people in developing countries. Children living in high risk areas of Konzo have high levels of glucosidase (linamarase) and low Rhodanesi microorganisms in their intestines. This can mean that they are more susceptible to disease and less protected. Nature Communication..

Konzo is a serious and irreversible neurological disorder that causes paralysis. This occurs after consuming contracted cassava, the root and the essential cassava crop for the Democratic Republic of Congo and other low-income countries. Insufficiently processed cassava contains linamarin cyanide. Enzymes with glucosidase activity convert starch into monosaccharides, but they also break down linamarin and release cyanide in the body.

“Knowing who is most at risk can lead to targeted interventions to better treat cassava and try to diversify our diets,” Children’s National said. Dr Eric Vilain, MD, director of the Center for Medical Genetics, said. “Another intervention is to modify the microbiome to increase the level of protection, but it is a daunting task that can have unintended consequences and other side effects.”

The exact biological mechanisms underlying the susceptibility and severity of conzo disease have not been fully understood. This is the first study to shed light on the gut microbiota Percentage of the population that depends on poisonous cassava as their main food source.

From left to right: Vincent Kambale and Dr Matthew Bramble. Here, liquid nitrogen is replenished in the tank containing the samples on the way from Kahemba to Kinshasa. Credit: Brambel et al. Nature Communications (2021), a national children’s hospital.

“Gut, since environment and malnutrition play a role, the gut microbiota is not the only cause of disease, but it is an essential regulator,” said Dr. Matthew S. Bramble, researcher at Children’s National. Declared. “Simply put, without the gut microbes, linamarin and other cyanide glycosides would pose little or no risk to humans.”

Harmful survival Gut microbiota And for their association with this debilitating multifactorial neurological disorder, the researchers used the shotgun metagenome sequence to compare the gut microflora profile of 180 children with CRD. This approach assesses bacterial diversity and detects the abundance of microbial and microbial genes in a variety of environments.

The composition and function of the gut microbiota may affect sensitivity to konzo, a neurological disorder caused by cassava, a staple food crop in the world.

Neerja Vashist is learning to breathe. Fufu is a traditional food made from cassava flour, and the cassava flour used here is moistened to further remove toxins from the cassava flour before consumption. .. Credit: Brambel et al. Nature Communications (2021), a national children’s hospital.

Samples were collected in Kinshasa. Urban area Varied meals and no konzo. Rural areas where the diet of majimanamba and cassava is predominant and the prevalence of konzo is low. And Kahemba is a region where the cassava diet is predominant and the prevalence of konzo is high.

“This study overcame many challenges in conducting the study. Low-resource environments Desire Tshala-Katumbay, MD, MPH, Ph.D., FANA, co-chief author and professional scientist at the National Institute of Biomedical in Kinshasa, Democratic Republic of the Congo, and professor of neurology in Oregon Health & Science University. States as follows. It will open up new avenues to prevent the Congo, a devastating disease for many children in sub-Saharan Africa. “

The composition and function of the gut microbiota may affect sensitivity to konzo, a neurological disorder caused by cassava, a staple food crop in the world.

From left to right: Dr Matthew Bramble, Vincent Kambale, Neerja Vashist. Here, the team processes samples in fields collected from the study cohort before storing them in liquid nitrogen. Credit: Brambel et al. Nature Communications (2021), a national children’s hospital.

For the next step, researchers are studying sibling pairs from conzos-prone areas of Kahemba, where only one sibling is affected.

“Studying siblings helps control factors that cannot be controlled otherwise. Cassava Dr. Neerja Vashist, PhD student and research intern at Children’s National, said: Over 40 million reads per sample and the size of the entire study cohort. This study design It can be confirmed that the trends we have observed are on a larger scale while improving the ability to comprehensively characterize the gut microbiota. ”


Scientists further support cassava research to help meet greater demand for food


For more information:
Konzo’s intestinal flora, Nature Communication (2021). doi.org/10.1038/s41467-021-25694-1

Provided by
National Children’s Hospital

Quote: The composition of the intestinal flora is taken from https://medicalxpress.com/news/2021-09-gut-flora-composition- September 10, 2021, the staple food of cassava (2021, September). 10 days) may affect susceptibility to conzo, a neurological disorder caused by Impact-susceptibility.html

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Gut bacteria build up common therapeutic drugs, study finds https://f-bod.com/gut-bacteria-build-up-common-therapeutic-drugs-study-finds/ Thu, 09 Sep 2021 00:39:00 +0000 https://f-bod.com/gut-bacteria-build-up-common-therapeutic-drugs-study-finds/ Common drugs can build up in gut bacteria, altering bacterial function and potentially reducing the drug’s effectiveness, according to a new study. These interactions – seen for a variety of drugs, such as drugs for depression, diabetes, and asthma – could help researchers better understand individual differences in drug efficacy and side effects, the study […]]]>

Common drugs can build up in gut bacteria, altering bacterial function and potentially reducing the drug’s effectiveness, according to a new study. These interactions – seen for a variety of drugs, such as drugs for depression, diabetes, and asthma – could help researchers better understand individual differences in drug efficacy and side effects, the study found. published in Nature.

It is known that bacteria can chemically alter certain drugs, a process known as biotransformation. This study, conducted by researchers from the Toxicology Unit of the Medical Research Council (MRC) at the University of Cambridge and the European Molecular Biology Laboratory (EMBL) in Germany, is the first to show that certain species of intestinal bacteria accumulate human drugs, altering the types of bacteria and their activity.

This could alter the effectiveness of the drug both directly, as the build-up could reduce the availability of the drug to the body, and indirectly, as altered bacterial function and composition could be linked to side effects.

The human gut naturally contains communities of hundreds of different species of bacteria, which are important for health and disease, called the gut microbiome. The composition of bacterial species varies widely from person to person and has already been shown to be associated with a wide range of conditions, including obesity, immune response, and mental health.

In this study, the researchers cultivated 25 common gut bacteria and studied their interaction with 15 drugs taken by mouth. The drugs were chosen to represent a range of different types of common drugs, including antidepressant drugs, which are known to affect people in different ways and cause side effects such as bowel problems and weight gain.

The researchers tested how each of the 15 drugs interacted with the selected bacterial strains – a total of 375 bacterial drug tests.

They found 70 interactions between the bacteria and the drugs studied – 29 of which had not been previously reported.

While previous research has shown that bacteria can chemically modify drugs, when scientists studied these interactions more deeply, they found that for 17 of the 29 new interactions, the drug accumulated in the bacteria without being changed.

Dr Kiran Patil, from the MRC Toxicology Unit at the University of Cambridge, who co-led the study, said: “It was surprising that the majority of the new interactions that we have seen between bacteria and drugs are the drugs that accumulate in bacteria, because until now, biotransformation was considered to be the primary means by which bacteria affect the availability of drugs. “

“These will likely be very personal differences between individuals, depending on the makeup of their gut microbiota. We have seen differences even between different strains of the same species of bacteria.”

Examples of drugs that have accumulated in bacteria include the antidepressant duloxetine and the antidiabetic rosiglitazone. For some drugs, such as montelukast (an asthma medicine) and roflumilast (for chronic obstructive pulmonary disease), the two changes occurred in different bacteria – they were accumulated by certain species of bacteria and changed by others.

They also found that the bioaccumulation of drugs alters the metabolism of the bacteria that accumulate. For example, the antidepressant drug duloxetine has bound to several metabolic enzymes in bacteria and altered their secreted metabolites.

The researchers developed a small community of several bacterial species together and found that the antidepressant duloxetine drastically altered the balance of the bacterial species. The drug altered the molecules produced by the drug-accumulating bacteria, which other bacteria feed on, so that the consuming bacteria grew much larger and upset the makeup of the community.

The researchers tested the effects further using C. elegans, a nematode worm commonly used to study intestinal bacteria. They studied duloxetine, which was found to accumulate in some bacteria but not in others. In worms cultured with the bacteria species that accumulate the drug, the behavior of the worms was altered after exposure to duloxetine, compared to worms cultured with bacteria that do not accumulate duloxetine.

EMBL’s Dr Athanasios Typas, who co-led the study, said: “It is only now that people recognize that drugs and our microbiome have a mutual impact with a critical consequence on our health. . “

Dr Peer Bork, EMBL and co-lead of the study, said: “It forces us to start treating the microbiome as one of our organs.”

Dr Patil said: “The next steps for us will be to advance this basic molecular research and study how an individual’s gut bacteria relate to different individual responses to drugs such as antidepressants – the differences depending on who. you answer, the dose of medication needed, and the side effects like weight gain. If we can characterize how people react based on their microbiome makeup, then drug treatments could be individualized.

The researchers warn that the study results relate only to bacteria grown in the laboratory and that more research is needed to understand how the bioaccumulation of drugs by gut bacteria manifests inside the human body.

The study started as a collaborative project at EMBL Heidelberg and ended in Kiran Patil’s group after his move to Cambridge. It involved researchers from the Typas, Bork, Zimmermann, Hennig, Schultz and Beck groups and the EMBL Savitski team, as well as central genomics, proteomics and metabolomics facilities from EMBL Heidelberg.

This study was funded by the European Commission Horizon 2020, MRC and EMBL.

Dr Megan Dowie, MRC’s Director of Molecular and Cellular Medicine said, “This study highlights the importance of the microbiome in drug delivery, efficacy and safety. be done to understand the important molecular aspects involved here, which could lead to a positive impact on an individual’s response to a range of commonly used drugs. “

Source:

Research and innovation in the UK

Journal reference:

Klünemann, M., et al. (2021) Bioaccumulation of therapeutic drugs by human intestinal bacteria. Nature. doi.org/10.1038/s41586-021-03891-8.


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